A Comparative Study on the Efficacy of Alvogyl, Neocone, Zinc Oxide Eugenol, and Iodoform Paste in the Management of Dry Socket
Abdul Rajjak Khandakar1, Ajay K Pillai2, Neha Jain3*, Dheeraj Sharma4, Tanushree Sahu5, Shubhi Lal6
1Resident, Dept of OMFS, Peoples Dental Academy, Peoples University Bhopal, India.
2Professor & HOD, Dept of OMFS, Peoples Dental Academy, Peoples University Bhopal, India.
3Professor, Dept of OMFS, Peoples Dental Academy, Peoples University Bhopal, India.
*Corresponding Author: Neha Jain, Professor, Dept of OMFS, Peoples Dental Academy, Peoples University Bhopal, India.
https://doi.org/10.58624/SVOADE.2025.06.018
Received: June 02, 2025
Published: July 02, 2025
Citation: Khandakar AR, Pillai AK, Jain N, Sharma D, Sahu T, Lal S. A Comparative Study on the Efficacy of Alvogyl, Neocone, Zinc Oxide Eugenol, and Iodoform Paste in the Management of Dry Socket. SVOA Dentistry 2025, 6:4, 108-116. doi: 10.58624/SVOADE.2025.06.018
Abstract
Introduction: Dry socket (alveolar osteitis) is a common, painful complication following tooth extraction, characterized by the loss of a stable blood clot and delayed healing. Despite various treatment options, there is no consensus on the most effective dressing material. This study aimed to compare the efficacy of Alvogyl, Neocone, Zinc Oxide Eugenol (ZOE), and Iodoform dressing in managing dry socket.
Materials and Methods: This prospective randomized study included 20 patients with clinically diagnosed with dry socket. Patients were randomly allocated into four groups (n=5 each): Group A (Alvogyl), Group B (ZOE), Group C (Neocone), and Group D (Iodoform dressing). Pain intensity was assessed using the Wong-Baker Visual Analogue Scale at multiple time points up to 10 days post-treatment. Clinical signs of healing, such as empty socket, exposed bone, and redness, were also evaluated. Statistical analyses included the Chi-square test, Z test for proportions, ANOVA, and Tukey HSD post-hoc tests.
Results: Alvogyl provided the fastest initial pain relief (mean 8.75 minutes), followed by Neocone, Iodoform, and ZOE. However, the shortest duration to complete pain relief was observed with Iodoform dressing (mean 4.2 days), followed by Neocone (4.9 days), Alvogyl (6.5 days), and ZOE (8.7 days). Neocone and Iodoform also demonstrated faster resolution of clinical signs, particularly in the healing of empty sockets and exposed bone.
Conclusion: While Alvogyl was most effective for rapid initial pain relief, Iodoform dressing and Neocone provided faster overall pain resolution and healing in dry socket cases.
Keywords: Dry Socket, Alveolar Osteitis, Alvogyl, Neocone, Zinc Oxide Eugenol, Iodoform Paste, Post-Extraction Complications, Pain Management
