Immunological Response to Respiratory Syncytial Virus Infection
Thyyar M Ravindranath*
*Corresponding Author: Thyyar M Ravindranath, MBBS, MS (Gen Surg), MD (Pediatrics and Pediatric Critical Care Medicine), Senior Lecturer, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Morgan Stanley Children’s Hospital of NewYork-Presbyterian, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, 630 West 168th Street, New York, New York-10032, USA.
DOI: https://doi.org/10.58624/SVOAPD.2023.02.039
Received: June 19, 2023 Published: July 10, 2023
Abstract
Immunological response to Respiratory Syncytial Virus (RSV) involves multiple entities such as cellular, antibody, cytokine, chemokine, and Pattern Recognizing Receptors (PRRs) that are mobilized to subdue the airway and pulmonary effects of the virus. RSV predominantly involves the respiratory tract including the bronchioles and the lungs in addition to the upper respiratory passage. Although RSV afflicts all age groups predominantly in winter, severe infection is more common in the very young and in older individuals, i.e., 60-65 years of age. Recently, vaccines and monoclonal antibodies have been developed as a preventive strategy for the vulnerable.
Keywords: RSV, T-cells, B-cells, cytokine, chemokine, PRRs.
Citation: Ravindranath Thyyar M. Immunological Response to Respiratory Syncytial Virus Infection. SVOA Paediatrics 2023, 2:4, 87-91.